13 - 12 BC – The Romans establish a military camp on the Kästrich
about 345 AD – Christianity comes to Mainz
after 400 – Mainz becomes Franconian
745 – Bonifatius (German apostle) is given the bishopric of Mainz. It is under his successor Lullus that Mainz becomes an archbishopric.
856 – Rabanus Maurus dies in Mainz
975 – 1011 -- Archbishop Willigis – Construction of St. Martins Cathedral
1002 – Bishop Willigis crowns Heinrich II in the Cathedral
about 1000 - 1802 – Mainz is an archbishopric. The archbishop of Mainz is the Arch chancellor of the German Empire, the highest ranking of the seven prince electors (responsible for selecting the king)
1184 – Emperor Barbarossa’s imperial festival
13th – 15th centuries -- Mainz is declared a free city
around 1440 –Johannes Gutenberg invents printing with movable type (Gutenberg Museum)
1452 - 1455 – Gutenberg prints the Gutenberg Bible in Mainz.
1462 – Archbishop Johann von Nassau loses Free City status. Mainz becomes a Residence City without self-governance.
1477 – The University is founded.
1792/93 – Mainz Republic
1798-1814 – Mainz belongs to France
1815 – Mainz becomes a Fortress of the German Federation
1826 – Steamboat company for the Middle Rhine is founded (tourist industry begins)
1837/38 – Beginning of the organised Fastnacht (Shrove Tuesday) festivities, with the Mainzer Ranzengarde 1837 and the Mainzer Karneval Verein 1838
1850-1877 – Bishop Ketteler
1853 – Mainz is linked to the railway network to the west of the Rhine
1872 – Major expansion of the city (the new part of Mainz)
1873 – Mainz becomes an Imperial fortification
1885 – Construction of the first fixed road bridge since antiquity
1904 – Closing down of the interior parts of the fortifications
1907 – First incorporation of a neighbouring town (Mombach)
1908 – Kastel and Amöneburg are incorporated
1913 – Kostheim is incorporated
after 1918 – all fortifications are dismantled
1930 – Weisenau, Bretzenheim, Bischofsheim and Ginsheim-Gustavsburg are incorporated.
1938 – Gonsenheim is incorporated
World War II – 80 percent of the centre of Mainz is destroyed
1945 – Splitting off of those parts of Mainz to the east of the Rhine (51 percent of the city’s municipal territory) by the American military administration. Temporary administration of Amöneburg, Kastel and Kostheim by the city of Wiesbaden
1946 – Reopening of the university in Mainz as the Johannes Gutenberg University
1950 – Mainz becomes the capital of Rhineland Palatinate
1962 – The ZDF television station establishes its headquarters in Mainz. Founding of Mainz-Lerchenberg (on the occasion of the 2000 year anniversary)
1969 - Drais, Ebersheim, Finthen, Hechtsheim, Laubenheim and Marienborn are incorporated.
1975 – 1000 year anniversary of St. Martins Cathedral
1977 – 500 year anniversary of the University of Mainz
1981 – Eleven Roman ships found from the Mainz Rhine Fleet of late antiquity
1990 – 1000 year anniversary of St. Stephan
1994 – Opening of the Museum for Ancient Shipping (Roman ship museum)
1995 – Completion of renovation work on the Theodor Heuss Bridge
1998 – Katholikentag (Catholics day) in Mainz
2000 – Mainz celebrates the 600th birthday of Johannes Gutenberg
2005 - 200 year anniversary of the municipal library